TAPUR Study: Testing FDA Approved Drugs Targeting Tumor Biomarkers in People with Advanced Stage Cancer

About the Study

The TAPUR Study is looking at the safety and efficacy of FDA-approved, targeted drugs to treat advanced cancers with certain tumor biomarkers. If interested, talk to your doctor about biomarker testing and visit www.tapur.org to find a participating center near you. Check here for the list of tumor mutations, markers and cancer types that are part of study eligibility. 

What the Study Involves

The TAPUR Study is looking at many different cancer types, biomarkers, and drugs all in the same clinical trial. The study has broad eligibility, collects the minimum necessary data, and allows for flexibility in visits, treatment decisions, and care decisions to better benefit the participants. Each cancer type and treatment type follows different treatment timelines, so speak with the study contact if you have questions about what would be required of you if you are eligible and decide to join the study.

More about the Study

The TAPUR Study is a phase II, nonrandomized clinical trial. Phase II means that the study looks at efficacy and side effects of the anticancer study treatments. Nonrandomized means that participants are not randomly divided into treatment groups.

Study Locations:

Alabama

Birmingham
University of Alabama at Birmingham Comprehensive Cancer Center- Birmingham
Contact: Misty Lowery; 205-644-2573; mmlowery@uabmc.edu

Arizona

Phoenix
Cancer Treatment Centers of America- Phoenix
Contact: Russell Fernandez; 623-207-3126; Russell.fernandez@ctca-hope.com

California

Kaiser Permanente- Oakland Medical Center- Oakland
Kaiser Permanente- Roseville Medical Center- Roseville
Kaiser Permanente- Sacramento Medical Center- Sacramento
Kaiser Permanente- South San Francisco Medical Center- San Francisco
Kaiser Permanente- San Francisco Medical Center- San Francisco
Kaiser Permanente- San Jose Medical Center- San Jose
Kaiser Permanente- San Leandro Medical Center- San Leandro
Kaiser Permanente- Santa Clara Medical Center- Santa Clara
Kaiser Permanente- Vallejo Medical Center- Vallejo
Kaiser Permanente- Walnut Creek Medical Center- Walnut Creek
Contact: Desiree Goldstein; desiree.goldstein@kp.org

California Pacific Medical Center Research Institute- San Francisco
Sutter Sacramento- Sacramento
Sutter Auburn- Auburn
Sutter Alta Bates- Berkeley
Sutter Roseville- Roseville
Sutter Palo Alto Medical Foundation- Palo Alto
Sutter Palo Alto Medical Foundation- Santa Cruz
Sutter Palo Alto Medical Foundation- Fremont
Sutter Palo Alto Medical Foundation- Sunnyvale
Contact: Juliana Van Cleve; 415-600-1654; Juliana.VanCleve@sutterhealth.org

The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate- Los Angeles
Contact: Saba Mukarram; 310-231-2181; smukkarm@theangelesclinic.org

Connecticut

Hartford Healthcare System

Saint Vincent’s Medical Center- Bridgeport
Hartford Hospital- Hartford
Midstate Medical Center- Midstate
The Hospital of Central Connecticut- New Britain
William W. Backus Hospital- Norwich
Charlotte Hungerford- Torrington
Windham Hospital- Willimantic
Contact: Melanie Manning; 860-972-5029; melanie.manning@hhchealth.org

Florida

Gainsville
University of Florida
Contact: Nghi Lam; 352-265-5329; Nghi.Lam@cancer.ufl.edu

Miami
University of Miami Sylvester Comprehensive Cancer Center
Contact: Carolina Troche; 305-243-1481; cxt582@med.miami.edu

Fort Lauderdale
Holy Cross Hospital
Contact: MCRCwebsitecontactform@trinity-health.org

Fort Myers
Florida Cancer Specialists South/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; Kristen.Borresen@flcancer.com  

Saint Petersburg
Florida Cancer Specialists North/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; Kristen.Borresen@flcancer.com  

Tallahassee
Florida Cancer Specialists Panhandle/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; Kristen.Borresen@flcancer.com  

West Palm Beach
Florida Cancer Specialists East/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; Kristen.Borresen@flcancer.com  

Georgia

Atlanta
Cancer Treatment Centers of America, Atlanta
Contact: Mittie Mitchell; 770-400-7194; Mittie.Mitchell@ctca-hope.com

Emory University Winship Cancer Institute
Contact: Suzanne Scott; 404-778-4083; Suzanne.e.scott@emory.edu

Savannah
Lewis Cancer and Research Pavilion
Summit Cancer Care
Gynecologic Oncology and Surgical Specialists at the Lewis Cancer and Research Pavilion
Lewis Cancer and Research Pavilion at the Melanoma, Skin Cancer, and Sarcoma Institute
Contact: Stephanie Smith; 912-819-5723; smiths1@sjchs.org

Hawaii

Honolulu
The Queen’s Medical Center (The University of Texas MD Anderson Cancer Center)
Contact: Amanda Eckert; 713-745-8074; ACEckert@mdanderson.org

Illinois

Chicago
Cancer Treatment Centers of America, Chicago
Contact: Rosielyn Sheridan; 847-872-4966; Rosielyn.sheridan@coh.org

Indiana

Indianapolis
Community Health Network (The University of Texas MD Anderson Cancer Center)
Contact: Amanda Eckert; 713-745-8074; ACEckert@mdanderson.org

Maine

Augusta
Jackson Laboratory- Main Cancer Genomics Initiative
Harold Alfond Center for Cancer Care
Contact: Sandra Neptune; 207-626-4811; Sandra.neptune@mainegeneral.org

Jackson Laboratory- Maine Cancer Genomics Initiative
Contact: Petra Helbig; 207- 664- 4659; Petra.Helbig@jax.org

Waldo County General Hospital- Belfast
SMHC Cancer Care and Blood Disorders- Biddeford
MaineHealth Cancer Care- Brunswick
Stephens Memorial Hospital- Norway
Penobscot Bay Medical Center- Rockport
SMHC Cancer Care and Blood Disorders, Sandford- Sandford
Maine Children’s Cancer Program- Scarborough
Maine Medical Partner’s Women’s Health- Scarborough
MaineHealth Cancer Care, South Portland- South Portland
Contact: Jen Dalton; 207- 294- 8291; JDalton@mmc.org

Northern Light Cancer Center- Brewer
Raish Peavy Haskell Children’s Cancer and Treatment Center- Brewer
Contact: Carla Mancini; 207-973-5581; cmancini@northernlight.org

New England Cancer Specialist- Kennebunk
New England Cancer Specialist- Scarborough
New England Cancer Specialist- Topsham
Contact: Patricia C. Collins; 207-303-3422; collip@newecs.org

York Hospital Oncology and Infusion Care in Kittery- Kittery
York Hospital Oncology and Infusion Care in Wells- Wells
York Hospital Oncology and Infusion Care in York- York
Contact: Branda Kilberd; 207-361-6115; Brenda.Kilberd@yorkhospital.com

Michigan

University of Michigan- Ann Arbor
Contact: Cancer AnswerLine Nurses; 800-865-1125; canceranswerline@umich.edu

Cancer Research Consortium of West Michigan- Grand Rapids
Ascension Borgess Cancer Center- Kalamazoo
Contact: Connie Szczepanek; 616-391-1230; crcwm-regulatory@crcwm.org
PI: Kathleen J. Yost, MD

Trinity Health Ann Arbor Hospital
Trinity Health Medical Center – Brighton
Trinity Health Medical Center – Canton
Chelsea Hospital – Chelsea
Trinity Health Oakland Hospital – Pontiac
Ascension St. John Hospital- Detroit
Van Elslander Cancer Center – Grosse Pointe Woods
Doctors Park – East China
Macomb Medical Campus – Macomb Township
Macomb Professional Building – Warren
Michigan Breast Specialists – Warren
Advanced Breast Care Center PLLC – Warren
Genesys Hurley Cancer Institute – Grand Blanc
Genesee Cancer and Blood Disease Treatment Center – Grand Blanc
Genesee Hematology Oncology, PC – Grand Blanc
Sparrow Hospital- Lansing
Ascension St. Mary’s Hospital- Saginaw
Oncology Hematology Associates of Saginaw Valley PC – Saginaw
Ascension Saint Joseph Hospital – Tawas City
Saint Mary’s Oncology/Hematology Associates of West Branch – West Branch
Trinity Health Livonia Hospital – Livonia
St. John Macomb Oakland Hospital- Warren
Contact: 734-712-7251; MCRCwebsitecontactform@trinity-health.org

Nebraska

University of Nebraska Medical Center- Omaha
Nebraska Medicine Bellevue Medical Center- Bellevue
Village Pointe (University of Nebraska Medical Center)- Omaha
Contact: Tannette Welsh; 402-552-3594; tannette.welsh@unmc.edu

New Hampshire

NH Oncology/Hematology- Concord
Solinsky Center for Cancer Care- Manchester
Contact: Ali Fleury; 603- 314- 6888; A.Fleury@nhoh.com

New England Cancer Specialists, Portsmouth
Contact: Patricia Collins; 207-303-3422; collip@newecs.org

New Mexico

Albuquerque
Lovelace Medical Center
Contact: Leslie Byatt; 505-925-0366; lpbyatt@salud.unm.edu

Presbyterian Kaseman Hospital
Contact: Monique Robertson; 505-559-6100; mrobertso2@phs.org

The University of New Mexico Comprehensive Cancer Center
Contact: Kawryn Gustafson; 505-925-0380; ksgustafson@salud.unm.edu

Las Cruces
Memorial Medical Center
Contact: Kim Hoffman; 575-556-6545; kim.hoffman@lpnt.net

Rio Rancho
Presbyterian Rust Medical Center
Contact: Andrea Yost; 505-253-7878; ayost3@phs.org

New York

Northwell Health Monter Cancer Center- Lake Success
Manhattan Eye, Ear, and Throat Hospital- New York
Cohen Children’s Medical Center- New Hyde Park
Phelps Hospital- Sleepy Hollow
Contact: Mary Agnes Templeton; 516-734-8979; mtetmpleton@northwell.edu

Herbert Irving Comprehensive Cancer Center- New York
Contact: Kim Roman; 212-342-3970; Lr2787@cumc.columbia.edu  

North Carolina

Chapel Hill
Lineberger Comprehensive Cancer Center
Contact: Emmie Cole; 919-966-4432; Emmie_cole@med.unc.edu

Charlotte
Atrium Health’s Levine Cancer Institute
Contact: Kelly Bumgarner; 704-403-2520; Kelly.Bumgarner@atriumhealth.org

North Dakota

Bismark
Sanford Health
Contact: Kassandra Remmel; 701-234-7515; Kassandra.remmel@sanfordhealth.org

Fargo
Sanford Health
Contact: Ellen Nelson; 701-234-7514; Ellen.Nelson@sanfordhealth.org

Ohio

University of Cincinnati Medical Center - Cincinnati
West Chester Hospital- West Chester
Contact: Kayla Webb; 513-584-0599; webb2ka@ucmail.uc.edu

Kettering Health- Kettering
Contact: Terri vanZant-Marvin; terri.vanzant-marvin@ketteringhealth.org

Oregon

Providence Health and Services- Portland
Contact: Isa Ngirailemesang; 971-358-2056; isa.ngirailemesang@providence.org

Pennsylvania

Lehigh Valley Health Network- Allentown
Lehigh Valley Hospital, Muhlenberg- Bethlehem
Lehigh Valley Hospital, Hazleton- Hazelton
Pocono Medical Center- East Stroudsburg
Contact: 734-712-7251; MCRCwebsitecontactform@trinity-health.org

Fox Chase Cancer Center- Philadelphia
Contact: Joan Aresco; 734-712-3304; Joan.Aresco@trinity-health.org

South Carolina

Levine Cancer Institute- Rock Hill
Contact: Kelly Bumgarner; 704-403-2520; Kelly.Bumgarner@atriumhealth.org

SC Cancer Specialists at St. Joseph’s Candler Bluffton- Bluffton
St. Joseph’s Candler Bluffton- Bluffton
Summit Cancer Care at St. Joseph’s/Candler Bluffton- Bluffton
South Carolina Cancer Specialists- Hilton Head Island
Contact: Stephanie Smith; 912-819-5723; smiths1@sjchs.org

South Dakota

Sanford Health- Sioux Falls
Contact: Michaela Melberg; 602-312-6229; Michaela.Melberg@sanfordhealth.org

Tennessee

Nashville
Tennessee Oncology, Nashville/ Sarah Cannon Research Institute
Contact: Ethan Trull; 615-329-7274; Ethan.Trull@SarahCannon.com

Texas

Houston
The University of Texas MD Anderson Cancer Center
Contact: Amanda Eckert, MPH; 713-745-8074; ACEckert@mdanderson.org

Utah

Dixie Regional Medical Center, River Road Campus- St. George
Dixie Regional Medical Center, 400 East Campus- St. George
Cedar City Hospital, SW Cancer Clinic, Sandra Maxwell Center- Cedar City
Contact: Rachel Pernick; 435-251-4743; Rachel.pernick@imail.org

Intermountain Precision Genomics Cancer Research Clinic- Salt Lake City
Contact: Tracy Taylor; 801-507-3953; tracy.taylor@imail.org

Virginia

Inova Schar Cancer Institute- Fairfax
Inova Fairfax Hospital- Fairfax
Inova Fair Oaks Hospital- Fairfax
IMG Oncology, Oncology GYN- Annandale
Contact: Roxana Comfort; 571-472-0624; Roxana.comfort@inova.org

Washington

Swedish Cancer Institute- Seattle
Swedish Cancer Institute, Ballard/Seattle- Seattle
Swedish Cancer Institute, Edmonds- Edmonds
Swedish Cancer Institute, First Hill/Seattle- Seattle
Swedish Cancer Institute, Gynecologic Oncology and Pelvic Surgery Clinic, First Hill- Seattle
Swedish Cancer Institute, Gynecologic Oncology and Pelvic Surgery Clinic, Issaquah- Issaquah
Swedish Cancer Institute, Issaquah- Issaquah
The Ben and Catherine Ivy Center for Advanced Brain Tumor- Seattle
Contact: Kimberly Reeves; 206-386-2227; Kimberly.reeves@swedish.org

Wisconsin

Aurora Cancer Care- Burlington
Aurora Health Care, Germantown Health Center- GermantowAurora Cancer Care- Grafton
Aurora BayCare Medical Center- Green BaAurora Cancer Care, Kenosha South- Kenosha
Aurora Bay Area Medical Center- Marinetta
Aurora Cancer Care- Milwaukee
Aurora St. Luke’s Medical Center- Milwaukee
Aurora Sinai Medical Center- Milwaukee
Aurora West Allis Medical Center- Milwaukee
Vince Lombardi Cancer Clinic- Oshkosh
Aurora Cancer Care- Racine
Vince Lombardi Cancer Center- Sheboygan
Aurora Medical Center- Summit
Vince Lombardi Cancer Clinic- Two Rivers
Aurora Cancer Center, Milwaukee West- Wauwatosa
Contact: Michelle Toutloff; 920-456-7880; Michelle.Martin2@aah.org

Lead Researchers/Study PIs and Affiliation

Richard Schilsky, MD, FACP, FSCT, FASCO TAPUR@asco.org