Pancreatic Cancer Screening Study (CAPS5)
Clinicaltrials.gov identifier:
NCT02000089
Prevention
Screening study for people at high risk for pancreatic cancer
Study Contact Information:
Hilary Cosby by phone 410-502-2893 or email: hcosby1@jhmi.edu
Pancreatic Cancer Screening Study (CAPS5)
About the Study
CAP5 is a study looking at screening for early cancer in people with an elevated lifetime risk of developing pancreatic cancer who are undergoing screening with esophageal , or . The goal is to study biomarkers derived from images and tissue samples (blood, pancreas fluid, duodenal fluid) for the early detection of pancreatic cancer and precancerous lesions.
What the Study Involves
Study participation involves:
- answering online questionnaires
- donating 4 tubes of blood- for research only
- (at some sites) collecting free standing fluid in the area where the pancreas drains fluid, aspirated by scope during EUS procedures- for research only.
- data from the participants medical record related to their pancreas screening and care.
- Optional: potential early detection blood test, collected annually. The CA19-9 result will be shared with the participant.
Study Locations
Connecticut
- New Haven
Contact: Scott Merenda by phone: 203-785-7019 or email: scott.merenda@yale.edu
Lead researcher: James Farrell, MD
Maryland
- Baltimore
Johns Hopkins Hospital
Contact: Hilary Cosby by phone 410-502-2893 or email: hcosby1@jhmi.edu
Lead researchers: Michael Goggins, MD and Marcia I Canto, MD
Massachusetts
- Boston
Dana Farber Cancer Center
Contact: Emily Blair by phone: 617-632-4788 or email: emily_blair@DFCI.Harvard.edu
Contact: Chinedu Ukaegbu by email: chinedu_ukaegbu@dfci.harvard.edu
Lead researcher: Sapna Syngal, MD
Michigan
- Ann Arbor, Michigan
University of Michigan
Contact: Erika Koeppe by phone: 734-998-1274 or email: eskoeppe@med.umich.edu
Researcher: Elena Stoffel, MD
New York
- New York City
Columbia University Medical Center
Contact: Tiffany Lam by email tl3141@cumc.columbia.edu
Lead researcher: Fay Kastrinos, MD
Ohio
- Cleveland
Case Comprehensive Cancer Center
Contact: Nancy Furrey by phone: 216-844-7314 or by email: nancy.furey@uhhospitals.org
Researcher: Amitabh Chak, MD
Pennsylvania
- Philadelphia
University of Pennsylvania
Contact: Maureen DeMarshall by phone: 215-349-8546 or email demarshm@mail.med.upenn.edu
Contact: Daniel Clay, email Daniel.Clay@Pennmedicine.upenn.edu
Researcher: Bryson Katona, MD - Pittsburgh
University of Pittsburgh
Contact: Christine Decapite by email: decapitec@upmc.edu
Contact: Nancy Abubaker by email: abubakern@upmc.edu
Lead researcher: Randall Brand, MD
This study is open to people at high risk for pancreatic cancer due to any of the following:
- in the following genes: , , FAMMM, , (, , , , ), hereditary pancreatitis (PRSS1/2, or CTRC), ()
- Strong family history of pancreas cancer on one side of the family tree or
- Endoscopic evaluation of pancreas scheduled
*contact your doctors or the study coordinators for a complete list of inclusion criteria.
This study is not open to people who:
- are unable to have an endoscopy
- are pregnant