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CDK4 Gene Mutations

Learn about the medical options for people with inherited CDK4 mutations.

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Information for People with an Inherited CDK4 Mutation

People with an in CDK4 have increased risk for melanoma and possibly pancreatic cancer. 

Experts have created guidelines which outline recommendations for managing risk in people with a CDK4 mutation. 

There may be family planning concerns and options for people with an inherited CDK4 mutation. 

Each of these topics is outlined in more detail in the sections highlighted below. 

More Information on CDK4 Mutations

Cancer Risks

Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for different cancers in people with inherited CDK4 mutations. 

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Risk Management Options

Read about the latest expert guidelines for cancer screening and prevention for people with a CDK4 mutation. Learn about research studies enrolling high-risk patients.  

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Cancer Treatment Options

Tumor  testing and genetic testing can provide additional clues about which treatments may work best for your cancer. People who test positive for a CDK4 mutation may have additional treatment or clinical trial options available to them. 

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Other Considerations

Learn additional information about inherited CDK4 mutations and options related to family planning. 

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More Resources

Last updated June 29, 2024